Endocrine Abstracts

Macroprolactin interference is a common problem in the interpretation of immunoassays for prolactin. Identifying macroprolactinemia can prevent errors in diagnosis and subsequent delivery of treatment to patients. The search for macroprolactin through polyethylene glycol (PEG) precipitation followed by percentage recovery is the most common used method in clinical laboratories. This study aimed to evaluate the implementation of macroprolactin assessment in hyperprolactinemic s...

: Elective central compartment neck dissection in the treatment of differentiated thyroid carcinomas (CDT) remains controversial. In a series of 1500 patients undergoing thyroid surgery, the authors evaluated the prognosis related to central compartment neck metastasis in differentiated microcarcinomas....

Background: Selenium (Se), a trace mineral with anti-oxidative properties, has been proposed to be potentially beneficial in patients with Graves’ disease (GD), especially those with active Graves’ ophthalmopathy (GO).Methods: Trials evaluating the efficacy of Se among non-pregnant adult GD patients with active GO, versus either placebo or an alternative drug, and on top of standard therapy, were included. A literature search was performed by t...

Our objective was to estimate the distribution of Spanish diabetic patients attending to individualized glycaemic targets recommended by the ADA/EASD consensus with and without considering hypoglycaemia risk. We conducted a cross-sectional study in a Spanish primary care setting between 2011 and 2012. A total of 5382 type 2 diabetic subjects under antihyperglycaemic treatment for at least 3 months prior to inclusion completed a study visit in which clinical data including age,...

Persistent Mullerian duct syndrome (PMDS) is a rare disorder of sex development characterized by the persistence of Mullerian duct derivatives in a genotypic (46,XY) and phenotypic normally virilised male. PMDS is transmitted in an autosomal recessive manner, caused by mutations in the anti-Mullerian hormone gene or in the gene encoding the AMH receptor. The authors report a case of a male patient aged 62 years, with bipolar disorder, referred to the endocrinologist by inciden...

Introduction: The usefulness of acute octreotide suppression test (OST) in the selection of patients with acromegaly for chronic somatostatin analogues (SA) treatment is still controversial.Aim: To investigate the predictive value of OST for long-term responsiveness to long-acting SA.Materials and methods: Retrospective study of 25 drug-naive patients (13 males) with active acromegaly, subjected to an OST (hourly serum GH concentra...

Introduction: The aim of this report is to present the uncommon clinical presentation of a patient with a pancreatic NET.Case report: A 55-year-old man with personal history of hypertension, dyslipidaemia, and depression. He was referred to the outpatient for high levels of calcium in repeated assessments during the last year. He referred polyuria and polydipsia. Not clinical history of bone fractures, abdominal pain, or another digestive symptoms. Initi...

Objective: To determine the degree of control of hypercholesterolemia in a specific lipid unit.Material and Methods: Retrospective study of patients followed in our unit over the past 16 years diagnosed with heterozygous familial hypercholesterolemia (HFH) or familial combined hyperlipidemia (FCH). Control criteria according to the following recommendations were compared: International Panel (2003), Nice (2008), NLA (2011), ESC / ESA 2011, Consensus ADA ...

Differentiated thyroid carcinoma is the most common endocrine malignant tumor. Papillary carcinoma frequency in our country is 80% of thyroid neoplasia. Papillary thyroid carcinoma usually metastasizes to cervical lymph. Metastases to distant organs are rare and most often affect the lungs, liver and bones. Despite of its anatomical proximity, metastasis parotid have not been described in the existing papillary carcinomas literature. We report a case of parotid gland metastasi...

Objective: Transition from pediatric to adult health care is a particularly vulnerable period for patients with inborn metabolic diseases.Our objective in this study was to evaluate the current transition of patients with phenylketonuria (PKU) in Malaga, Spain, by analysis of the metabolic control, medical care, patients satisfaction and phychosocial status.Material and methods: We evaluate all the patients transferred to our adult...